William H. Wallace House, located at 430 East Main Street in Union, South Carolina, is a historic residence constructed around 1850. It is a contributing property within the East Main Street–Douglass Heights Historic District, which was added to the National Register of Historic Places in 1989.

This two-story stuccoed brick residence features:

• A one-story arcaded porch supported by brick pillars, added around 1909.
• A double-door entrance with sidelights and a fanlight adorned with alternating voussoirs.
• Dentil molding on window and door surrounds.

These elements contribute to the house’s distinctive appearance within the historic district.

Built for Charles Kaiser, a local jeweler, the house was purchased in 1857 by William H. Wallace, a prominent figure in Union County. Wallace was a planter, lawyer, publisher, and Confederate brigadier general during the Civil War. After the war, he served in the South Carolina House of Representatives from 1872 to 1877, was appointed as a circuit judge in 1877, and held the position until his retirement in 1893.

On April 28, 1865, Confederate President Jefferson Davis and his entourage dined at the Wallace House during their retreat through South Carolina. This event is commemorated by a historical marker at the site.

As a private residence, the William H. Wallace House is not open to the public. However, its architectural features can be appreciated from the street. Visitors are encouraged to view the exterior respectfully from public sidewalks or roads.