Holmewood House is a historic residence located in Edgefield, South Carolina, notable for its association with Governor Milledge Luke Bonham. Bonham served as the 70th Governor of South Carolina from 1862 to 1864 during the Civil War.

Holmewood was constructed between 1827 and 1832 by William Prothro, a prominent planter, timberman, mill owner, and businessman. The house features a Greek Revival style with a white clapboard exterior, six columns supporting the front portico, and a double-door entrance with a semicircular fanlight. The property was listed on the National Register of Historic Places on October 14, 1971. ​

In 1865, following the Civil War, Bonham resided at Holmewood with his family. He had previously lived at Darby Plantation, another historic property in Edgefield County. Bonham’s tenure at Holmewood was during the Reconstruction era, a period of significant political and social change in the South. ​

While Holmewood is a private residence and not open to the public, it remains a significant landmark in Edgefield’s rich historical tapestry. For those interested in exploring Edgefield’s history, the Edgefield County Historical Society offers resources and information on various historic homes and sites in the area.