The property is part of the Seneca Historic District, which was added to the National Register of Historic Places on December 31, 1974, with a boundary expansion in 1987. It is listed at 210 S. Townville Street within that district. Like many homes in the district, it likely showcases popular styles from the era—American Foursquare, Bungalow/Craftsman, or Late Victorian—though the exact style isn’t specified in the register. The district overall contains around 20 residential properties, featuring late-19th-century and pre-WWI designs in styles such as Victorian, Classical Revival, Foursquare, Craftsman, and Tudor Revival.

The district, and by extension the H. L. Thompson House, represents Seneca’s architectural growth and development between the late 1800s and early 1900s. The house itself likely belonged to a member of the Thompson family—an early name in the town’s founding and subdivision sale after railroad establishment in 1873.