The Blocker House is a historic plantation house located near Edgefield, Edgefield County, South Carolina built circa 1790 by John Blocker, Sr. It is a two-story, clapboard dwelling with a one-story shed-roofed porch supported by four square columns. The property includes centuries old magnolia and cedar trees, a family cemetery, and several outbuildings.

It was listed on the National Register of Historic Places in 1971.