Lowther Hall is a historic residence located in Pendleton, South Carolina. Originally built around 1793 for Dr. William Hunter, the property was purchased in 1815 by William Lord Viscount Lowther, a British Treasury official. The estate was later expanded in 1895 by William Henry Trescott. ​

The home is featured on the Pendleton Historic Walking Tour, highlighting its architectural significance and historical context within the town.