The Western Carolina Bank, built around 1910, was a notable establishment in Johnston, South Carolina. It featured a standard design used by the bank across the state and was considered one of the best examples of this design.

Today, the building is part of the Johnston Historic District, which includes other significant structures like the Johnston Depot, H.W. Crouch Building, and the Bank of Johnston (now Jone’s Coin Laundry).

Currently, Regions Bank operates a branch in Johnston, offering a range of personal and business banking services.