Allison Plantation is a historic home and farm complex located near York, York County, South Carolina. The main house was built about 1860, and is a 2+1⁄2-story, frame Greek Revival style dwelling. It has a two-room one-story frame ell and two-story pedimented portico supported by square columns. Also on the property are a one-story frame barn, remains of the detached log kitchen, a concrete pedestal for a windmill, a spring house, smokehouse, mill, and the dilapidated remains of Dr. Allison’s Drugstore. It was the home of Dr. Robert Turner Allison, a locally prominent physician and politician.
It was added to the National Register of Historic Places in 1980.